OEM Fluidic Solutions

Precision Piston Pumps
for HPLC & FPLC.

CRS Scientific engineers high-performance reciprocating piston pumps trusted by chromatography instrument manufacturers worldwide — from analytical to preparative scale, from research to GMP biopurification.

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0.001–1000ml/min flow range
up to 60 MPaworking pressure
< 0.1%flow rate accuracy

Engineered for global instrument brands across

Analytical HPLC UHPLC Preparative HPLC FPLC / Bio-LC Flash Chromatography SFC & SMB
Why CRS

Built for the demands of modern chromatography.

Every CRS pump is designed around one principle: deliver clean, pulse-free, repeatable flow under the most challenging chemistries and the longest duty cycles.

Ultra-low pulsation

Dual reciprocating piston architecture with synchronized cam profiling delivers a stable baseline — even at sub-µL/min flow rates.

Bioinert flow path

PEEK, titanium, and ceramic wetted parts protect biomolecules — purpose-built for FPLC, protein purification, and high-salt buffers.

Modular OEM form factor

Compact mechanical envelope, standardized fluidic ports, and CAN/RS-485/UART control interfaces drop straight into your instrument.

Pressure to 60 MPa

Hardened sapphire plungers, dual check valves, and high-tension seals withstand UHPLC backpressures without sacrificing seal life.

Self-learning compensation

Adaptive compressibility correction and real-time pressure feedback keep gradient composition accurate across solvent systems.

Documentation & support

Full integration kits: mechanical drawings, communication protocol docs, sample firmware, and regulatory documentation for IVDR/FDA submissions.

Product Families

A pump series for every chromatography platform.

Analytical

CRS-HP Series

0.001 – 10 ml/min · 60 MPa

Dual-piston analytical pump engineered for HPLC and UHPLC OEM platforms requiring sub-percent retention time reproducibility.

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Preparative

CRS-FB Series

1 – 300 ml/min · 30 MPa

High-flow preparative piston pumps with extended seal life — ideal for purification, flash chromatography, and scale-up.

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FPLC / Bio

CRS-MBio Series

0 – 150 ml/min · up to 25 MPa · 3 models

Fully bioinert FPLC pump family with washed plunger seals — protecting proteins, peptides, and nucleic acids across low, medium, and high-flow workflows.

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Industrial

CRS-LP Series

10 – 1000 ml/min · 15 MPa

Large-volume metering pumps for process-scale chromatography, SMB, and continuous biomanufacturing skids.

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OEM Partnership

Your instrument. Our pump platform.

From early concept through volume production, CRS Scientific functions as an extension of your engineering team. We co-develop mechanical envelopes, electrical interfaces, and fluidic schemes that match your product roadmap — and we back it with consistent, audited manufacturing.

  • Private-label branding and bespoke configurations
  • ISO 9001 manufacturing with traceable serialization
  • Long-term supply agreements and EOL protection
  • On-site engineering support for integration
See the OEM process →
15+ Years building OEM pumps for chromatography
40+ Instrument brands integrating CRS pumps
3000+ Pumps shipped to OEM customers annually
< 8 wk From custom spec to engineering samples

Ready to specify your next OEM pump?

Send us your flow envelope, pressure target, and integration constraints — we'll respond with a configuration and timeline within two business days.

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